Tricarboxylic acids and derivatives
Medchemexpress LLC Tos-peg3-ch2cooh | 1581248-63-6 | 100 MG
Tos-PEG3-CH2COOH is a PEG-based PROTAC linker designed for use in the synthesis of PROTACs. PROTACs are molecules that leverage the intracellular ubiquitin-proteasome system to selectively degrade target proteins. They consist of two different ligands connected by a linker; one ligand binds to an E3 ubiquitin ligase, and the other binds to the target protein, facilitating its degradation.
- Utilizes the ubiquitin-proteasome system for selective protein degradation.
- Acts as a linker in the construction of degraders.
Electron Microscopy Sciences Ammonium Alcohol 500 ML
Used in Alizarin Red S and Toluidine Blue O for distinction of bone and cartilage in mammalian embryos. See Dawson A.B., Stain Techn., 1:123-4, 1926, Williams, T.W., Stain Techn., 16:23-5, 1941, or Clark, G., (ed), Staining Procedures, 3rd Ed., Williams & Wilkins Baltimore, p. 139, c. 1973
Medchemexpress LLC HY-W016813 100mg Medchemexpress, trans-Aconitic acid CAS:4023-65-8 Purity:>98%
Medchemexpress, HY-W016813 100mg trans-Aconitic acid CAS:4023-65-8 trans-Aconitic acid is present in normal human urine, and it has been suggested that is present in larger amounts with Reye's syndrome and organic aciduria. trans-Aconitic acid is a substrate of enzyme trans-aconitate 2-methyltransferase. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC Amino-PEG5-CH2COOH | 141282-35-1 | ≥97.0% | 500 MG
Amino-PEG5-CH2COOH is a PEG-based PROTAC linker used in the synthesis of PROTACs. PROTACs contain two distinct ligands connected by a linker; one targets an E3 ubiquitin ligase and the other targets the protein. They function by exploiting the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- PEG-based PROTAC linker
- Targets PROTAC linkers within the PROTAC pathway
- Solid appearance
- White to off-white color
- Store at 4°C, protected from light
- In solvent, store at -80°C for 6 months or -20°C for 1 month, protected from light
Medchemexpress LLC Tos-PEG3-CH2COOH | 1581248-63-6 | 50 MG
Tos-PEG3-CH2COOH is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. These PROTACs feature two distinct ligands connected by a linker: one targets an E3 ubiquitin ligase, and the other binds to a specific target protein. This mechanism allows PROTACs to exploit the intracellular ubiquitin-proteasome system for the selective degradation of target proteins. This product is for research use only.
- PEG-based PROTAC linker
- Used for PROTAC synthesis
- Leverages ubiquitin-proteasome system
- Selectively degrades target proteins
- For research use only
Medchemexpress LLC Bromo-PEG1-CH2COOH | 1135131-50-8 | ≥97.0% | 250 MG
Bromo-PEG1-CH2COOH is a PROTAC linker instrumental in the synthesis of Proteolysis Targeting Chimeras (PROTACs). These PROTACs function by connecting two distinct ligands-one targeting an E3 ubiquitin ligase and the other a protein of interest-thereby exploiting the intracellular ubiquitin-proteasome system to achieve selective degradation of target proteins.
- Used in the synthesis of PROTACs
- Connects two different ligands
- Designed for selective degradation of target proteins
- Exploits the intracellular ubiquitin-proteasome system
- For research use only
Medchemexpress LLC Subasumstat | 1858276-04-6 | 578.10 | 100 MG
Subasumstat (TAK-981) is a first-in-class and selective inhibitor of the SUMOylation enzymatic cascade, demonstrating potential immune-activating and antineoplastic activities. It increases the production of type 1 IFN, enhancing type 1 IFN-mediated signaling, activating innate effector cells, and improving antitumor innate immune responses. A single subcutaneous injection induces activation of dendritic cells.
- First-in-class selective inhibitor of SUMOylation enzymatic cascade
- Potential immune-activating activities
- Potential antineoplastic activities
- Increases production of type 1 IFN
- Enhances antitumor innate immune responses
- Activates innate effector cells
- Induces activation of dendritic cells
Medchemexpress LLC Adenosine 5'-(α,β-methylene)diphosphate triammonium | 99.9% | 476.32 | 50 MG
MethADP triammonium is a CD73 inhibitor that can be used for research of the ATP-adenosine pathway. It inhibits 5'-AMP induced adenosine formation in A498 cells at concentrations of 20 and 100 μmol/L. It is for research use only and not sold to patients.
- Inhibits 5'-AMP induced adenosine formation in A498 cells.
- For research use only.
- Off-white to light yellow solid.
- Store at 4°C, sealed, away from moisture and light.
- Store in solvent at -80°C for 6 months or -20°C for 1 month.
eMolecules 267221-90-9 | Tris(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)amine | MFCD28098209 | 250mg
Ambeed | (R)-2-Hydroxypent-4-ene | 250mg | 553634464 | A915630 | 64584-92-5 | MFCD03701536 | 86.134 | C5H10O
If you are unable to find the chemical you are looking for, make sure you are logged into your fishersci.com account and click on the following link:
eMolecules Building Block Tool<|a>
![Alkali Scientific 4 Methylumbelliferyl B D glucopyranoside Monohydrate [Methylumbelliferyl B D glucoside], 10 G](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000660125.jpg-250.jpg)
Alkali Scientific 4 Methylumbelliferyl B D glucopyranoside Monohydrate [Methylumbelliferyl B D glucoside], 10 G
Methylumbelliferyl β-D Glucopyranoside Monohydrate, 10 g is a biochemical reagent used for the study of glucosidase enzyme activity. This substrate is hydrolyzed by glucosidases to release a fluorescent product, making it an essential tool for enzyme assays, diagnostic tests, and research into metabolic processes. The high purity and sensitivity of this reagent make it ideal for use in microbiology, clinical diagnostics, and genetic research, where detecting small quantities of enzyme activity is crucial. It is particularly useful in enzyme kinetics studies and applications requiring accurate and high-sensitivity measurements of glucosidase activity.
Medchemexpress LLC 2'-deoxyuridine-5'-triphosphate trisodium salt | 102814-08-4 | MFCD00084701 | 99.7% | 534.09 | C9H12N2Na3O14P3 | 5 MG
dUTP trisodium (2'-deoxyuridine-5'-triphosphate trisodium salt) is the trisodium salt of dUTP, a deoxynucleotide triphosphate used as a dTTP substitute in PCR and related enzymatic applications to produce uracil-containing DNA. Supplied as a solid with high reported purity, it is intended for workflows that require uracil incorporation or UDG-based carryover prevention.
- High purity (99.74%) suitable for sensitive enzymatic reactions.
- Provided as a white to off-white solid, 5 mg pack size.
- Trisodium salt form for stable handling and solubility.
- Compatible with PCR and RT-PCR to produce uracil-containing PCR products.
- Supports uracil-DNA glycosylase (UDG)-based carryover prevention.
- Store sealed, away from moisture; in solution: -80°C (up to 6 months), -20°C (up to 1 month).
Medchemexpress LLC IACS-8803 diammonium | 00-00-0 | 96.7% | C20H29FN12O9P2S2 | 10MG
IACS-8803 (diammonium) is a cyclic dinucleotide STING agonist supplied as a diammonium salt for research use. It potently activates the STING pathway and has demonstrated robust systemic antitumor efficacy in preclinical studies. The diammonium salt improves handling and stability compared with the free form and is intended for in vitro and in vivo immuno-oncology research.
- Potent STING pathway agonist for immune activation.
- Demonstrated systemic antitumor efficacy in preclinical models.
- Suitable for in vitro and in vivo research applications.
- Diammonium salt formulation for improved stability and handling.
- Requires cold-chain storage; research use only.
Medchemexpress LLC Oxolamine citrate (SKF-9976 citrate) | 1949-20-8 | 99.9% | 1 ML
Oxolamine citrate (SKF-9976 citrate) is an orally active antitussive that can inhibit CYP2B1/2 and has anti-inflammatory effects on the respiratory organs of guinea pigs. It increases the AUC of Warfarin and prolongs its terminal half-life. It can be used in respiratory disease research.
- Orally active antitussive
- Inhibits CYP2B1/2
- Has anti-inflammatory effects on the respiratory organs of guinea pigs
- Increases the AUC of Warfarin and prolongs its terminal half-life
- Can be used in respiratory disease research
Medchemexpress LLC Triammonium phosphate trihydrate | 25447-33-0 | MFCD00151223 | ≥98.0% | 203.13 | H18N3O7P | 100g
Triammonium phosphate trihydrate interacts with the magnesium ions to form a precipitate which can be used for magnesium separation from lithium in salt-lake brines[1]