Tricarboxylic acids and derivatives
Medchemexpress LLC Adenosine 5'-(α,β-methylene)diphosphate triammonium | 99.9% | 476.32 | 50 MG
MethADP triammonium is a CD73 inhibitor that can be used for research of the ATP-adenosine pathway. It inhibits 5'-AMP induced adenosine formation in A498 cells at concentrations of 20 and 100 μmol/L. It is for research use only and not sold to patients.
- Inhibits 5'-AMP induced adenosine formation in A498 cells.
- For research use only.
- Off-white to light yellow solid.
- Store at 4°C, sealed, away from moisture and light.
- Store in solvent at -80°C for 6 months or -20°C for 1 month.
![Alkali Scientific 4 Methylumbelliferyl B D glucopyranoside Monohydrate [Methylumbelliferyl B D glucoside], 10 G](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000660125.jpg-250.jpg)
Alkali Scientific 4 Methylumbelliferyl B D glucopyranoside Monohydrate [Methylumbelliferyl B D glucoside], 10 G
Methylumbelliferyl β-D Glucopyranoside Monohydrate, 10 g is a biochemical reagent used for the study of glucosidase enzyme activity. This substrate is hydrolyzed by glucosidases to release a fluorescent product, making it an essential tool for enzyme assays, diagnostic tests, and research into metabolic processes. The high purity and sensitivity of this reagent make it ideal for use in microbiology, clinical diagnostics, and genetic research, where detecting small quantities of enzyme activity is crucial. It is particularly useful in enzyme kinetics studies and applications requiring accurate and high-sensitivity measurements of glucosidase activity.
Medchemexpress LLC 2'-deoxyuridine-5'-triphosphate trisodium salt | 102814-08-4 | MFCD00084701 | 99.7% | 534.09 | C9H12N2Na3O14P3 | 5 MG
dUTP trisodium (2'-deoxyuridine-5'-triphosphate trisodium salt) is the trisodium salt of dUTP, a deoxynucleotide triphosphate used as a dTTP substitute in PCR and related enzymatic applications to produce uracil-containing DNA. Supplied as a solid with high reported purity, it is intended for workflows that require uracil incorporation or UDG-based carryover prevention.
- High purity (99.74%) suitable for sensitive enzymatic reactions.
- Provided as a white to off-white solid, 5 mg pack size.
- Trisodium salt form for stable handling and solubility.
- Compatible with PCR and RT-PCR to produce uracil-containing PCR products.
- Supports uracil-DNA glycosylase (UDG)-based carryover prevention.
- Store sealed, away from moisture; in solution: -80°C (up to 6 months), -20°C (up to 1 month).
Medchemexpress LLC (E/Z)-zotiraciclib citrate | 1204918-73-9 | 99.8% | 564.59 g/mol | C29H32N4O8 | 10 MG
(E/Z)-Zotiraciclib citrate is the citrate salt form of zotiraciclib, a small-molecule kinase inhibitor active against CDK2, JAK2, and FLT3. It is supplied as an off-white to light yellow solid for laboratory research use, and is characterized by high purity and defined storage guidance for both solid and solution forms.
- Potent inhibitor of CDK2, JAK2, and FLT3, suitable for kinase research.
- Citrate salt form with molecular weight 564.59 g/mol.
- Chemical formula C29H32N4O8.
- High purity (≈99.8%), appropriate for biochemical and cell-based assays.
- Solid physical form: off-white to light yellow powder.
- Recommended storage sealed, away from moisture; freeze solutions for long-term storage.
- Offered in multiple pack sizes, including small milligram quantities and solution formats for convenience.
![eMolecules 68-04-2 | Sodium citrate, anhydrous | Oakwood Chemical | MFCD00012462 | 258.068 | C6H5Na3O7 | 99.000 | [Na+].[Na+].[Na+].OC(CC([O-])=O)(CC([O-])=O)C([O-])=O | 25g | 866847505](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000470643.jpg-250.jpg)
eMolecules 68-04-2 | Sodium citrate, anhydrous | Oakwood Chemical | MFCD00012462 | 258.068 | C6H5Na3O7 | 99.000 | [Na+].[Na+].[Na+].OC(CC([O-])=O)(CC([O-])=O)C([O-])=O | 25g | 866847505
Sodium citrate, anhydrous | Oakwood Chemical | 68-04-2 | MFCD00012462 | 258.068 | C6H5Na3O7 | 99.000 | [Na+].[Na+].[Na+].OC(CC([O-])=O)(CC([O-])=O)C([O-])=O | 25g | 866847505
Medchemexpress LLC 5,8,11,14,17,20-Hexaoxa-2-azadocosanedioic acid, 1-(9H-fluoren-9-ylmethyl) ester | 437655-96-4 | 99.4% | 1 G
Fmoc-NH-PEG6-CH2COOH is a cleavable linker used in the synthesis of antibody-drug conjugates (ADCs). It also functions as a PEG-based PROTAC linker, applicable in the synthesis of PROTACs. This compound facilitates the controlled degradation of target proteins by exploiting the intracellular ubiquitin-proteasome system.
- Cleavable linker for ADC synthesis
- PEG-based PROTAC linker
- Utilizes ubiquitin-proteasome system
- Enables selective degradation of target proteins
- Molecular weight of 561.62
- Formula C29H39NO10
- Appearance: colorless to light yellow liquid
- Soluble in DMSO (100 mg/mL)
Medchemexpress LLC Acetic acid, 2-[2-(2-azidoethoxy)ethoxy]- | 882518-90-3 | 99.03% | 189.17 | 10 MG
Azido-PEG2-CH2COOH is a PEG-based PROTAC linker designed for use in the synthesis of PROTACs. It also functions as a click chemistry reagent, featuring an Azide group that can participate in copper-catalyzed azide-alkyne cycloaddition reactions (CuAAc) with molecules containing Alkyne groups. Additionally, it can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
- Can be used in the synthesis of PROTACs.
- Functions as a click chemistry reagent.
- Azide group enables copper-catalyzed azide-alkyne cycloaddition.
- Can undergo strain-promoted alkyne-azide cycloaddition with DBCO or BCN groups.
Apexbio Technology LLC Orphenadrine Citrate 4682-36-4 10mM (in 1mL DMSO)
Orphenadrine Citrate (CAS 4682-36-4) is a small molecule utilized in biomedical research for its pharmacological modulation of neurological pathways It acts by inhibiting the binding of [ 3H]MK-801 to the phencyclidine (PCP) site of the N-methyl-D-aspartate (NMDA) receptor in human frontal cortex tissue implicating antagonism at NMDA-type glutamate receptors Orphenadrine has historically served as an antiparkinsonian antispastic and analgesic agent Its ability to modulate NMDA receptor activity makes it a valuable tool for studies investigating glutamatergic neurotransmission and related neuropharmacological mechanisms
Medchemexpress LLC 5,8,11,14,17,20-hexaoxa-2-azadocosanedioic acid, 1-(9H-fluoren-9-ylmethyl) ester | 437655-96-4 | MFCD26142983 | 99.4% | 561.62 g/mol | C29H39NO10 | 50 MG
Fmoc-NH-PEG6-CH2COOH is an Fmoc-protected PEG6 linker bearing a terminal carboxylic acid and an Fmoc-protected amine. It is used as a hydrophilic spacer in the synthesis of proteolysis targeting chimeras (PROTACs) and antibody-drug conjugates (ADCs), providing solubility and a reactive handle for amide coupling.
- Fmoc-protected amine for orthogonal protection in synthesis.
- Terminal carboxylic acid suitable for amide coupling.
- PEG6 spacer increases hydrophilicity and solubility.
- High reported purity (≈99.4%).
- Available in multiple package sizes for milligram to gram scale work.
Medchemexpress LLC Amino-PEG5-CH2COOH | 141282-35-1 | ≥97.0% | 500 MG
Amino-PEG5-CH2COOH is a PEG-based PROTAC linker used in the synthesis of PROTACs. PROTACs contain two distinct ligands connected by a linker; one targets an E3 ubiquitin ligase and the other targets the protein. They function by exploiting the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- PEG-based PROTAC linker
- Targets PROTAC linkers within the PROTAC pathway
- Solid appearance
- White to off-white color
- Store at 4°C, protected from light
- In solvent, store at -80°C for 6 months or -20°C for 1 month, protected from light
Medchemexpress LLC Triammonium phosphate trihydrate | 25447-33-0 | MFCD00151223 | ≥98.0% | 203.13 | H18N3O7P | 1kg
Triammonium phosphate trihydrate interacts with the magnesium ions to form a precipitate which can be used for magnesium separation from lithium in salt-lake brines[1]
Medchemexpress LLC Tos-PEG3-CH2COOH | 1581248-63-6 | 50 MG
Tos-PEG3-CH2COOH is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. These PROTACs feature two distinct ligands connected by a linker: one targets an E3 ubiquitin ligase, and the other binds to a specific target protein. This mechanism allows PROTACs to exploit the intracellular ubiquitin-proteasome system for the selective degradation of target proteins. This product is for research use only.
- PEG-based PROTAC linker
- Used for PROTAC synthesis
- Leverages ubiquitin-proteasome system
- Selectively degrades target proteins
- For research use only